The Frequency of myocarditis in patients with COVID-19 and in-hospital mortality.

Myocarditis and COVID.19

Authors

  • Muhammad Zahid Ali Nawaz Sharif Medical College, Gujrat, Punjab, Pakistan
  • Irfan Younus Bhatti Rajput Nawaz Sharif Medical College, Gujrat, Punjab, Pakistan
  • Sohail Yousaf Punjab Institute of Cardiology, Lahore, Pakistan
  • Muhammad Javed Nawaz Sharif Medical College, Gujrat, Punjab, Pakistan
  • Khalil Iqbal Nawaz Sharif Medical College, Gujrat, Punjab, Pakistan
  • Faiza Altaf Aziz Bhatti Shaheed Hospital, Gujrat, Punjab, Pakistan

Keywords:

COVID-19, Myocarditis, in-hospital mortality

Abstract

Objective: To determine the frequency of myocarditis in patients with COVID-19 and in-hospital mortality.

Study design: Observational cohort study.

Study setting and duration: Fifty five patients between 15-70 years of age, admitted in corona ward of Aziz Bhatti Shaheed Teaching Hospital, Nawaz Sharif Medical College, Gujrat from 15 to 30th march 2020.

Material and methods: Patients with positive PCR results for covid-19 were included in this study after informed consent; patients with prior history of any cardiovascular, pulmonary or other co-morbidity were excluded while patients having history of hypertension, diabetes or smoking were included in the study. All the patients remain admitted for 14 days. Patients were evaluated clinically, by ECG, troponins and echocardiographically for diagnosis of myocarditis. Patients were managed conservatively. Incidence of myocarditis and in-hospital mortality was noted. Successful treatment towards hospital discharge was relief of clinical symptoms, a-febrile, clear chest X-Ray and at least two consecutive negative PCR for covid-19. p value <0.05 was considered as significant. Data was analyzed with SPSS -23.

Results:  Out of fifty five, 5(9%) patients were diabetics and 4 were hypertensive. Five (9%) developed mild pneumonia which recovered conservatively and three (5.4%) patients developed myocarditis. One (1.8%) patient expired having myocarditis. Duration of follow up was only during hospital stay. So our in-hospital mortality was 1.8%, p value was calculated as significant < 0.05.

Conclusion: Myocarditis is a known but less common complication of COVID-19. Cardiac injury is more in those with previously having cardiovascular or other co-morbidities. In healthy and immunocompetent population its incidence is quite low.

Author Biographies

Muhammad Zahid Ali, Nawaz Sharif Medical College, Gujrat, Punjab, Pakistan

Assistant Professor Cardiology

Irfan Younus Bhatti Rajput, Nawaz Sharif Medical College, Gujrat, Punjab, Pakistan

Assistant Professor of Gastroenterology

Sohail Yousaf, Punjab Institute of Cardiology, Lahore, Pakistan

Senior Registrar Cardiology

Muhammad Javed, Nawaz Sharif Medical College, Gujrat, Punjab, Pakistan

Assistant Professor of Anaesthesia

Khalil Iqbal, Nawaz Sharif Medical College, Gujrat, Punjab, Pakistan

Assistant Professor of Anaesthesia

Faiza Altaf, Aziz Bhatti Shaheed Hospital, Gujrat, Punjab, Pakistan

Medical Officer 

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Published

2021-08-05