ASSOCIATION OF WAIST-HIP RATIO WITH SEVERE CORONARY ARTERY DISEASE IN PATIENTS UNDERGOING CORONARY ANGIOGRAPHY IN A TERTIARY CARE HOSPITAL

Abstract

Introduction: Association of increased waist-hip ratio with severe coronary artery disease has not been determined among our local population. As changing lifestyles have affected anthropometric measurements of population, these associations need to be addressed.

Objective: Objectives were to determine the association of increased waist-hip ratio with the severity of coronary artery disease.

Study Design: Case control study

Study Setting: Study was conducted in Department of Cardiology, Jinnah Hospital, Lahore.

Materials and Methods: Total of 360 patients of male population were enrolled in the study.180 male cases having severe coronary artery disease (stenosis of > 50% in a major epicardial coronary artery) were taken and increased waist-hip ratio was determined. It was assessed at the time of inclusion into study. Similarly, 180 male controls were taken from same population. A waist-hip ratio of more than 0.95 was taken as increased waist-hip ratio. Odds ratio was calculated to determine the association of increased waist hip ratio with severe coronary artery disease.

Results: In our sampled population, when we cross tabulated cases and controls with waist to hip ratio above 0.95, we came up with an odd ratio (OR) of 3.49 at p value of 0.028 (significant). It showed that Waist/Hip ratio > 0.95 had not equally distributed among cases and controls. There was significant effect of being smoker but no effect of being obese and family history of coronary artery disease on this association. 

Conclusion: It is concluded that in our sampled population we reject the null hypothesis that there is no association of increased waist-hip ratio with severe coronary artery disease and accept the alternate hypothesis that there is an association found between Waist/Hip ratio > 0.95, as odds ratio came out 3.5 with P value=0.02 (Significant).