Correlation of CT angiography and Doppler ultrasonography in diagnosing peripheral arterial disease

Authors

  • Saman Nosheen Islamabad Diagnostic Centre, Islamabad
  • Zeeshan Ghias Khan DHQ Hospital Gahkuch, Ghizer, Gilgit Baltistan
  • Muzammil Rasheed Bhutta Shaukat Khanum Memorial Cancer Hospital, Lahore
  • Najeeb Ullah Bolan Medical College, Quetta, Balochistan, Pakistan
  • Shahrukh Faisal Ghurki Trust and Teaching Hospital, Lahore
  • Muhammad Yousuf Skeikh Khalifa Bin Zayyed Hospital, Quetta

DOI:

https://doi.org/10.55958/jcvd.v20i1.165

Keywords:

Peripheral arterial disease, ultrasound, angiography

Abstract

Introduction: Doppler ultrasound (DUS) has limitations in evaluating peripheral arterial disease (PAD) in complex areas like the adductor canal, morbidly obese patients, and those with severe limb swelling or ulcers. Compared to computed tomographic angiography (CTA) and magnetic resonance angiography (MRA), DUS shows lower sensitivity. CTA and MRA offer excellent diagnostic capabilities for PAD.

Objectives: This study aimed to assess the agreement between CT angiography and Doppler ultrasonography in diagnosing PAD.

Materials and Methods: A cross-sectional study was conducted at the Department of Radiology, Bolan Medical Complex, Quetta from March 20, 2021, to September 19, 2021. We included 100 patients (aged 20-60 years) referred for suspected PAD. Patients with diabetes, impaired kidney function, and pregnancy were excluded. DUS examinations were performed by on-duty radiologists, assessing blood flow in lower limb arteries from the distal external iliac/common femoral artery to the dorsalis pedis artery. Results were compared with the patients' subsequent CTA findings, performed by the radiology department's CT team. Both teams were blinded to the study to minimize bias.

Results: CT angiography confirmed PAD in 58 (58%) patients. DUS identified 54 true positives and 7 false positives. Among patients with negative DUS findings, 4 were false negatives, and 35 were true negatives (p-value=0.0001). The agreement between CT angiography and DUS for PAD diagnosis was 89.0%, with a kappa value of 0.772.

Conclusion: This study demonstrates good agreement between CT angiography and Doppler ultrasonography in diagnosing peripheral arterial disease.

Author Biographies

Saman Nosheen, Islamabad Diagnostic Centre, Islamabad

Consultant Radiologist

Zeeshan Ghias Khan, DHQ Hospital Gahkuch, Ghizer, Gilgit Baltistan

Consultant Radiologist

Najeeb Ullah, Bolan Medical College, Quetta, Balochistan, Pakistan

Sonologist

Shahrukh Faisal, Ghurki Trust and Teaching Hospital, Lahore

Casualty Medical Officer

Muhammad Yousuf, Skeikh Khalifa Bin Zayyed Hospital, Quetta

Senior Registrar

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Published

2024-06-06

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Section

Articles