Measuring Major Adverse Cardiovascular Events (MACE) in male vs female suffering from acute ST-Elevation Myocardial Infarction undergoing Primary Percutaneous Coronary Intervention (PPCI) at PIC, Lahore
Keywords:Primary PCI, Acute STEMI, MACE
Worldwide, Coronary Artery Diseases (CADs) cause significant disability and death. Primary PCI (PPCI) is the gold-standard of emergency care in management of patients suffering from STEMI. Gender-based differences may be present in the major cardiovascular outcomes (MACE) of PPCI.
This article aims at comparing major adverse cardiovascular outcomes male vs female STEMI patients going through PPCI.
Descriptive case series
Emergency Department, Punjab Institute of Cardiology (PIC), Lahore.
With mean age just over 50.3 ± 9.7 years, 193 (78.8%) males and 52 (21.2%) female, a total of 245 patients were enrolled in the study. Risk factors included diabetes, hypertension, familial IHD and active smoking. We recorded in-hospital outcomes post-pPCI: mortality, cerebrovascular accident, acute and subacute stent thrombosis, heart failure, acute kidney injury and arrhythmias.
Post PPCI in-hospital outcomes in 193 males: mortality 0, heart failure 3 (1.6%), acute stent thrombosis 0 and acute kidney injury in 11 patients (5.7%). Among 52 females: mortality 2 (3.8%), heart failure 2 (3.8%), acute stent thrombosis 1 (1.9%) and acute kidney injury 3 (5.8%). The only significant association was found between female gender & post PPCI mortality after STEMI (P = 0.006).
Results of in-hospital complications among male & female patients following PPCI for acute STEMI seem to show association of female gender with post-PPCI mortality which is significantly greater than the male population under study.
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